A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth

Signals from the apical ectodermal ridge (AER) of the developing vertebrate limb, including fibroblast growth factor-8 (FGF-8), can maintain limb mesenchymal cells in a proliferative state. We report here that a specific CD44 splice variant is crucial for the proliferation of these mesenchymal cells...

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Bibliografische Detailangaben

Veröffentlicht in:	Genes Dev
Hauptverfasser:	Sherman, Larry, Wainwright, David, Ponta, Helmut, Herrlich, Peter
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 1998
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9531542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.7.1058
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