A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth

Signals from the apical ectodermal ridge (AER) of the developing vertebrate limb, including fibroblast growth factor-8 (FGF-8), can maintain limb mesenchymal cells in a proliferative state. We report here that a specific CD44 splice variant is crucial for the proliferation of these mesenchymal cells...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Genes Dev
Autori principali:	Sherman, Larry, Wainwright, David, Ponta, Helmut, Herrlich, Peter
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 1998
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9531542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.7.1058
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!