A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth

Signals from the apical ectodermal ridge (AER) of the developing vertebrate limb, including fibroblast growth factor-8 (FGF-8), can maintain limb mesenchymal cells in a proliferative state. We report here that a specific CD44 splice variant is crucial for the proliferation of these mesenchymal cells...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Sherman, Larry, Wainwright, David, Ponta, Helmut, Herrlich, Peter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1998
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9531542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.7.1058
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