TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

Bone resorption and remodeling is an intricately controlled, physiological process that requires the function of osteoclasts. The processes governing both the differentiation and activation of osteoclasts involve signals induced by osteoprotegerin ligand (OPGL), a member of tumor necrosis factor (TN...

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Autori principali: Lomaga, Mark A., Yeh, Wen-Chen, Sarosi, Ildiko, Duncan, Gordon S., Furlonger, Caren, Ho, Alexandra, Morony, Sean, Capparelli, Casey, Van, Gwyneth, Kaufman, Stephen, van der Heiden, Annette, Itie, Annick, Wakeham, Andrew, Khoo, Wilson, Sasaki, Takehiko, Cao, Zhaodan, Penninger, Josef M., Paige, Christopher J., Lacey, David L., Dunstan, Colin R., Boyle, William J., Goeddel, David V., Mak, Tak W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1999
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC316636/
https://ncbi.nlm.nih.gov/pubmed/10215628
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