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Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

Plasmodium spp parasites harbor an unusual plastid organelle called the apicoplast. Due to its prokaryotic origin and essential function, the apicoplast is a key target for development of new anti-malarials. Over 500 proteins are predicted to localize to this organelle and several prokaryotic bioche...

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Bibliographic Details
Main Authors: Yeh, Ellen, DeRisi, Joseph L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166167/
https://ncbi.nlm.nih.gov/pubmed/21912516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001138
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