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Impact of Host Genes and Strand Selection on miRNA and miRNA* Expression

Dysregulation of miRNAs expression plays a critical role in the pathogenesis of genetic, multifactorial disorders and in human cancers. We exploited sequence, genomic and expression information to investigate two main aspects of post-transcriptional regulation in miRNA biogenesis, namely strand sele...

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Main Authors: Biasiolo, Marta, Sales, Gabriele, Lionetti, Marta, Agnelli, Luca, Todoerti, Katia, Bisognin, Andrea, Coppe, Alessandro, Romualdi, Chiara, Neri, Antonino, Bortoluzzi, Stefania
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166117/
https://ncbi.nlm.nih.gov/pubmed/21909367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023854
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