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Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans

Mutations in the Caenorhabditis elegans separase gene, sep-1, are embryonic lethal. Newly fertilized mutant embryos have defects in polar body extrusion, fail to undergo cortical granule exocytosis, and subsequently fail to complete cytokinesis. Chromosome nondisjunction during the meiotic divisions...

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Bibliografiska uppgifter
Huvudupphovsmän: Richie, Christopher T., Bembenek, Joshua N., Chestnut, Barry, Furuta, Tokiko, Schumacher, Jill M., Wallenfang, Matthew, Golden, Andy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Company of Biologists 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166036/
https://ncbi.nlm.nih.gov/pubmed/21878498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.073379
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