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Protease-Dead Separase Is Dominant Negative in the C. elegans Embryo
Separase is a protease that promotes chromosome segregation at anaphase by cleaving cohesin. Several non-proteolytic functions of separase have been identified in other organisms. We created a transgenic C. elegans line that expresses protease-dead separase in embryos to further characterize separas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4171520/ https://ncbi.nlm.nih.gov/pubmed/25244427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108188 |
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