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Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans

Mutations in the Caenorhabditis elegans separase gene, sep-1, are embryonic lethal. Newly fertilized mutant embryos have defects in polar body extrusion, fail to undergo cortical granule exocytosis, and subsequently fail to complete cytokinesis. Chromosome nondisjunction during the meiotic divisions...

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Detalhes bibliográficos
Main Authors: Richie, Christopher T., Bembenek, Joshua N., Chestnut, Barry, Furuta, Tokiko, Schumacher, Jill M., Wallenfang, Matthew, Golden, Andy
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166036/
https://ncbi.nlm.nih.gov/pubmed/21878498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.073379
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