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Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans
Mutations in the Caenorhabditis elegans separase gene, sep-1, are embryonic lethal. Newly fertilized mutant embryos have defects in polar body extrusion, fail to undergo cortical granule exocytosis, and subsequently fail to complete cytokinesis. Chromosome nondisjunction during the meiotic divisions...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Company of Biologists
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166036/ https://ncbi.nlm.nih.gov/pubmed/21878498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.073379 |
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