The RecBC enzyme loads RecA protein onto ssDNA asymmetrically and independently of χ, resulting in constitutive recombination activation

Double-strand DNA break repair and homologous recombination in Escherichia coli proceed by the RecBCD pathway, which is regulated by cis-acting elements known as χ sites. A crucial feature of this regulation is the RecBCD enzyme-directed loading of RecA protein specifically onto the 3′-terminal, χ-c...

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Bibliografiska uppgifter
Huvudupphovsmän: Churchill, Jason J., Anderson, Daniel G., Kowalczykowski, Stephen C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 1999
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC316600/
https://ncbi.nlm.nih.gov/pubmed/10197989
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