The RecBC enzyme loads RecA protein onto ssDNA asymmetrically and independently of χ, resulting in constitutive recombination activation

Double-strand DNA break repair and homologous recombination in Escherichia coli proceed by the RecBCD pathway, which is regulated by cis-acting elements known as χ sites. A crucial feature of this regulation is the RecBCD enzyme-directed loading of RecA protein specifically onto the 3′-terminal, χ-c...

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Vydáno v:	Genes Dev
Hlavní autoři:	Churchill, Jason J., Anderson, Daniel G., Kowalczykowski, Stephen C.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Cold Spring Harbor Laboratory Press 1999
Témata:	Research Paper
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10197989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.7.901
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