The RecBC enzyme loads RecA protein onto ssDNA asymmetrically and independently of χ, resulting in constitutive recombination activation
Double-strand DNA break repair and homologous recombination in Escherichia coli proceed by the RecBCD pathway, which is regulated by cis-acting elements known as χ sites. A crucial feature of this regulation is the RecBCD enzyme-directed loading of RecA protein specifically onto the 3′-terminal, χ-c...
Shranjeno v:
| izdano v: | Genes Dev |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10197989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.7.901 |
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