The RecBC enzyme loads RecA protein onto ssDNA asymmetrically and independently of χ, resulting in constitutive recombination activation

Double-strand DNA break repair and homologous recombination in Escherichia coli proceed by the RecBCD pathway, which is regulated by cis-acting elements known as χ sites. A crucial feature of this regulation is the RecBCD enzyme-directed loading of RecA protein specifically onto the 3′-terminal, χ-c...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Churchill, Jason J., Anderson, Daniel G., Kowalczykowski, Stephen C.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1999
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10197989/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.7.901
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