Comprehensive Proteomic Analysis of Influenza Virus Polymerase Complex Reveals a Novel Association with Mitochondrial Proteins and RNA Polymerase Accessory Factors

The trimeric RNA polymerase complex (3P, for PA-PB1-PB2) of influenza A virus (IAV) is an important viral determinant of pathogenicity and host range restriction. Specific interactions of the polymerase complex with host proteins may be determining factors in both of these characteristics and play i...

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Main Authors: Bradel-Tretheway, Birgit G., Mattiacio, Jonelle L., Krasnoselsky, Alexei, Stevenson, Catherine, Purdy, David, Dewhurst, Stephen, Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165779/
https://ncbi.nlm.nih.gov/pubmed/21715506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00496-11
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