High-Functional-Avidity Cytotoxic T Lymphocyte Responses to HLA-B-Restricted Gag-Derived Epitopes Associated with Relative HIV Control

Virus-specific cytotoxic T lymphocytes (CTL) with high levels of functional avidity have been associated with viral clearance in hepatitis C virus infection and with enhanced antiviral protective immunity in animal models. However, the role of functional avidity as a determinant of HIV-specific CTL...

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Autori principali: Berger, Christoph T., Frahm, Nicole, Price, David A., Mothe, Beatriz, Ghebremichael, Musie, Hartman, Kari L., Henry, Leah M., Brenchley, Jason M., Ruff, Laura E., Venturi, Vanessa, Pereyra, Florencia, Sidney, John, Sette, Alessandro, Douek, Daniel C., Walker, Bruce D., Kaufmann, Daniel E., Brander, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165743/
https://ncbi.nlm.nih.gov/pubmed/21752903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00460-11
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