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A Conditional Mouse Model for Measuring the Frequency of Homologous Recombination Events In Vivo in the Absence of Essential Genes

The ability to detect and repair DNA damage is crucial to the prevention of various diseases. Loss of function of genes involved in these processes is known to result in significant developmental defects and/or predisposition to cancer. One such DNA repair mechanism, homologous recombination, has th...

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Detalhes bibliográficos
Main Authors: Brown, Adam D., Claybon, Alison B., Bishop, Alexander J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165555/
https://ncbi.nlm.nih.gov/pubmed/21709021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00848-10
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