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A Conditional Mouse Model for Measuring the Frequency of Homologous Recombination Events In Vivo in the Absence of Essential Genes

The ability to detect and repair DNA damage is crucial to the prevention of various diseases. Loss of function of genes involved in these processes is known to result in significant developmental defects and/or predisposition to cancer. One such DNA repair mechanism, homologous recombination, has th...

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書誌詳細
主要な著者: Brown, Adam D., Claybon, Alison B., Bishop, Alexander J. R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165555/
https://ncbi.nlm.nih.gov/pubmed/21709021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00848-10
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