Pharmacokinetics and Ex Vivo Antimalarial Activity of Artesunate-Azithromycin in Healthy Volunteers

In 18 male healthy subjects, artesunate (200 mg)-azithromycin (1,500 mg) daily for 3 days was found to be well tolerated, with only mild gastrointestinal disturbances reported. The pharmacokinetic properties of artesunate-azithromycin given in combination are comparable to those of the drugs given a...

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Main Authors: Chinh, Nguyen Trong, Quang, Nguyen Ngoc, Anh, Chu Xuan, Thanh, Nguyen Xuan, Dai, Bui, Birrell, Geoffrey W., Chavchich, Marina, Edstein, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165334/
https://ncbi.nlm.nih.gov/pubmed/21730120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00365-11
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