Comparison of the Pharmacokinetics and Ex Vivo Antimalarial Activities of Artesunate–Amodiaquine and Artemisinin–Piperaquine in Healthy Volunteers for Preselection Malaria Therapy

The pharmacokinetics (PK) and ex vivo activity (pharmacodynamics [PD]) of two artemisinin combination therapies (ACTs) (artemisinin–piperaquine [ARN–PPQ] [Artequick(®)] and artesunate–amodiaquine [ARS–AQ] [Coarsucam(™)]) in healthy Vietnamese volunteers were compared following 3-day courses of the A...

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Publicat a:Am J Trop Med Hyg
Autors principals: Quang, Nguyen Ngoc, Chavchich, Marina, Anh, Chu Xuan, Birrell, Geoffrey W., van Breda, Karin, Travers, Thomas, Rowcliffe, Kerryn, Edstein, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Tropical Medicine and Hygiene 2018
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085815/
https://ncbi.nlm.nih.gov/pubmed/29741150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.17-0434
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