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puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila

The activation of MAPKs is controlled by the balance between MAPK kinase and MAPK phosphatase activities. The latter is mediated by a subset of phosphatases with dual specificity (VH-1 family). Here, we describe a new member of this family encoded by the puckered gene of Drosophila. Mutations in thi...

詳細記述

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書誌詳細
出版年:Genes Dev
主要な著者: Martín-Blanco, Enrique, Gampel, Alexandra, Ring, Jenny, Virdee, Kanwar, Kirov, Nikolai, Tolkovsky, Aviva M., Martinez-Arias, Alfonso
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316530/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9472024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.4.557
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