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The Drosophila Pkn protein kinase is a Rho/Rac effector target required for dorsal closure during embryogenesis

The PKN family of PKC-related protein kinases constitutes the major Rho GTPase-associated protein kinase activities detected in mammalian tissues. However, the biological functions of these kinases are unknown. We have identified a closely related PKN homolog in Drosophila (Pkn) that binds specifica...

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Bibliographic Details
Main Authors: Lu, Yu, Settleman, Jeffrey
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316938/
https://ncbi.nlm.nih.gov/pubmed/10323867
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