puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila

The activation of MAPKs is controlled by the balance between MAPK kinase and MAPK phosphatase activities. The latter is mediated by a subset of phosphatases with dual specificity (VH-1 family). Here, we describe a new member of this family encoded by the puckered gene of Drosophila. Mutations in thi...

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izdano v:	Genes Dev
Principais autores:	Martín-Blanco, Enrique, Gampel, Alexandra, Ring, Jenny, Virdee, Kanwar, Kirov, Nikolai, Tolkovsky, Aviva M., Martinez-Arias, Alfonso
Format:	Artigo
Jezik:	Inglês
Izdano:	Cold Spring Harbor Laboratory Press 1998
Teme:	Research Paper
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9472024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.4.557
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