Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G(1) cell cycle arrest of human breast cancer cells

Lignende værker

• 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells
  af: Nguyen, Hanh H., et al.
  Udgivet: (2010)
• Indole-3-Carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells
  af: Marconett, Crystal N., et al.
  Udgivet: (2012)
• Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop
  af: Marconett, Crystal N., et al.
  Udgivet: (2010)
• Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells
  af: Tin, Antony S, et al.
  Udgivet: (2014)
• Hypoxia-Inducible Factor 1 Mediates Upregulation of Telomerase (hTERT)
  af: Nishi, Hirotaka, et al.
  Udgivet: (2004)