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Alzheimer's risk variants in the clusterin gene are associated with alternative splicing
Genetic variation in CLU encoding clusterin has been associated with Alzheimer's disease (AD) through replicated genome-wide studies, but the underlying mechanisms remain unknown. Following earlier reports that tightly regulated CLU alternative transcripts have different functions, we tested CL...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3165035/ https://ncbi.nlm.nih.gov/pubmed/21892414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2011.17 |
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