Minimization and Optimization of Designed β-Hairpin Folds

Mimimized β hairpins have provided additional data on the geometric preferences of Trp interactions in TW-loop-WT motifs. This motif imparts significant fold stability to peptides as short as 8 residues. High-resolution NMR structures of a 16- (KKWTWNPATGKWTWQE, ΔG(U)(298) ≥ +7 kJ/mol) and 12-residu...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Andersen, Niels H., Olsen, Katherine A., Fesinmeyer, R. Matthew, Tan, Xu, Hudson, F. Michael, Eidenschink, Lisa A., Farazi, Shabnam R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164952/
https://ncbi.nlm.nih.gov/pubmed/16669679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja054971w
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares