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Stabilizing capping motif for β-hairpins and sheets

Although much has been learned about the design of models of β-sheets during the last decade, modest fold stabilities in water and terminal fraying remain a feature of most β-hairpin peptides. In the case of hairpin capping, nature did not provide guidance for solving the problem. Some observations...

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Bibliografiske detaljer
Main Authors: Kier, Brandon L., Shu, Irene, Eidenschink, Lisa A., Andersen, Niels H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890817/
https://ncbi.nlm.nih.gov/pubmed/20484672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913534107
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