Down-regulation of Glutathione S-transferase Pi in Asthma Contributes to Enhanced Oxidative Stress

BACKGROUND: Glutathione S-transferase Pi (GSTPi) is the predominant redox regulator in the lung. While evidence implicates an important role for GSTPi in asthma, the mechanism for this has remained elusive. OBJECTIVES: To determine how GSTPi is regulated in asthma and to elucidate its role in mainta...

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Auteurs principaux: Schroer, Kathy T., Gibson, Aaron M., Sivaprasad, Umasundari, Bass, Stacey A., Ericksen, Mark B., Wills-Karp, Marsha, LeCras, Tim, Fitzpatrick, Anne M., Brown, Lou Ann S., Stringer, Keith F., Khurana Hershey, Gurjit K.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164907/
https://ncbi.nlm.nih.gov/pubmed/21570714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.04.018
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