Using azobenzene incorporated DNA aptamers to probe molecular binding interactions

The rational design of DNA/RNA aptamers for use as molecular probes depends on a clear understanding of their structural elements in relation to target-aptamer binding interactions. We present a simple method to create aptamer probes that can occupy two different structural states. Then, based on th...

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Autori principali: Phillips, Joseph A., Liu, Haipeng, O’Donoghue, Meghan B., Xiong, Xiangling, Wang, Ruowen, You, Mingxu, Sefah, Kwame, Tan, Weihong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164881/
https://ncbi.nlm.nih.gov/pubmed/21247152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100402p
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