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Using photons to manipulate enzyme inhibition by an azobenzene-modified nucleic acid probe

The ability to inhibit an enzyme in a specific tissue with high spatial resolution combined with a readily available antidote should find many biomedical applications. We have accomplished this by taking advantage of the cis–trans photoisomerization of azobenzene molecules. Specifically, we position...

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Detalhes bibliográficos
Main Authors: Kim, Youngmi, Phillips, Joseph A., Liu, Haipeng, Kang, Huaizhi, Tan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672545/
https://ncbi.nlm.nih.gov/pubmed/19359478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812402106
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