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Superior structure stability and selectivity of hairpin nucleic acid probes with an l-DNA stem

Hairpin nucleic acid probes have been highly useful in many areas, especially for intracellular and in vitro nucleic acid detection. The success of these probes can be attributed to the ease with which their conformational change upon target binding can be coupled to a variety of signal transduction...

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Detalhes bibliográficos
Main Authors: Kim, Youngmi, Yang, Chaoyong James, Tan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175343/
https://ncbi.nlm.nih.gov/pubmed/17959649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm771
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