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DNA aptamer–micelle as an efficient detection/delivery vehicle toward cancer cells

We report the design of a self-assembled aptamer–micelle nanostructure that achieves selective and strong binding of otherwise low-affinity aptamers at physiological conditions. Specific recognition ability is directly built into the nanostructures. The attachment of a lipid tail onto the end of nuc...

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Detalhes bibliográficos
Main Authors: Wu, Yanrong, Sefah, Kwame, Liu, Haipeng, Wang, Ruowen, Tan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806697/
https://ncbi.nlm.nih.gov/pubmed/20080797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909611107
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