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Quantum Chemical Study of the Mechanism of Action of Vitamin K Carboxylase in Solvent
We investigate the post-translational generation of Gla (γ-carboxy glutamic acid) from Glu (glutamic acid) by vitamin K carboxylase (VKC) in solvent. VKC is thought to convert vitamin K, in the vitamin K cycle, to an alkoxide-epoxide form, which then reacts with CO(2) to generate an essential ingred...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164839/ https://ncbi.nlm.nih.gov/pubmed/21892230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/qua.22740 |
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