Drosophila IAP1-Mediated Ubiquitylation Controls Activation of the Initiator Caspase DRONC Independent of Protein Degradation

Ubiquitylation targets proteins for proteasome-mediated degradation and plays important roles in many biological processes including apoptosis. However, non-proteolytic functions of ubiquitylation are also known. In Drosophila, the inhibitor of apoptosis protein 1 (DIAP1) is known to ubiquitylate th...

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Bibliographic Details
Main Authors: Lee, Tom V., Fan, Yun, Wang, Shiuan, Srivastava, Mayank, Broemer, Meike, Meier, Pascal, Bergmann, Andreas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164697/
https://ncbi.nlm.nih.gov/pubmed/21909282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002261
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