Sequential Bottlenecks Drive Viral Evolution in Early Acute Hepatitis C Virus Infection

Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and liver disease. The characterization of viral populations that successfully initiate infection, and also those that drive progression to chronicity is instrumental for understanding pathogenesis and vaccine design....

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Autors principals: Bull, Rowena A., Luciani, Fabio, McElroy, Kerensa, Gaudieri, Silvana, Pham, Son T., Chopra, Abha, Cameron, Barbara, Maher, Lisa, Dore, Gregory J., White, Peter A., Lloyd, Andrew R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164670/
https://ncbi.nlm.nih.gov/pubmed/21912520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002243
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