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Accurate single nucleotide variant detection in viral populations by combining probabilistic clustering with a statistical test of strand bias
BACKGROUND: Deep sequencing is a powerful tool for assessing viral genetic diversity. Such experiments harness the high coverage afforded by next generation sequencing protocols by treating sequencing reads as a population sample. Distinguishing true single nucleotide variants (SNVs) from sequencing...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848937/ https://ncbi.nlm.nih.gov/pubmed/23879730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-501 |
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