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Transmitted/Founder Viruses Rapidly Escape from CD8(+) T Cell Responses in Acute Hepatitis C Virus Infection

The interaction between hepatitis C virus (HCV) and cellular immune responses during very early infection is critical for disease outcome. To date, the impact of antigen-specific cellular immune responses on the evolution of the viral population establishing infection and on potential escape has not...

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Publicado en:J Virol
Autores principales: Bull, Rowena A., Leung, Preston, Gaudieri, Silvana, Deshpande, Pooja, Cameron, Barbara, Walker, Melanie, Chopra, Abha, Lloyd, Andrew R., Luciani, Fabio
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442533/
https://ncbi.nlm.nih.gov/pubmed/25740982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03717-14
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