Sequential Bottlenecks Drive Viral Evolution in Early Acute Hepatitis C Virus Infection

Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and liver disease. The characterization of viral populations that successfully initiate infection, and also those that drive progression to chronicity is instrumental for understanding pathogenesis and vaccine design....

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Autores principales: Bull, Rowena A., Luciani, Fabio, McElroy, Kerensa, Gaudieri, Silvana, Pham, Son T., Chopra, Abha, Cameron, Barbara, Maher, Lisa, Dore, Gregory J., White, Peter A., Lloyd, Andrew R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164670/
https://ncbi.nlm.nih.gov/pubmed/21912520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002243
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