Imaging Long-Term Fate of Intramyocardially Implanted Mesenchymal Stem Cells in a Porcine Myocardial Infarction Model

The long-term fate of stem cells after intramyocardial delivery is unknown. We used noninvasive, repetitive PET/CT imaging with [(18)F]FEAU to monitor the long-term (up to 5 months) spatial-temporal dynamics of MSCs retrovirally transduced with the sr39HSV1-tk gene (sr39HSV1-tk-MSC) and implanted in...

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Detalhes bibliográficos
Main Authors: Perin, Emerson C., Tian, Mei, Marini, Frank C., Silva, Guilherme V., Zheng, Yi, Baimbridge, Fred, Quan, Xin, Fernandes, Marlos R., Gahremanpour, Amir, Young, Daniel, Paolillo, Vincenzo, Mukhopadhyay, Uday, Borne, Agatha T., Uthamanthil, Rajesh, Brammer, David, Jackson, James, Decker, William K., Najjar, Amer M., Thomas, Michael W., Volgin, Andrei, Rabinovich, Brian, Soghomonyan, Suren, Jeong, Hwan-Jeong, Rios, Jesse M., Steiner, David, Robinson, Simon, Mawlawi, Osama, Pan, Tinsu, Stafford, Jason, Kundra, Vikas, Li, Chun, Alauddin, Mian M., Willerson, James T., Shpall, Elizabeth, Gelovani, Juri G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164664/
https://ncbi.nlm.nih.gov/pubmed/21912635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022949
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