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The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

The ordered progression through the cell cycle depends on regulating the abundance of several proteins through ubiquitin-mediated proteolysis. Degradation is precisely timed and specific. One key component of the degradation system, the anaphase promoting complex (APC), is a ubiquitin protein ligase...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Pfleger, Cathie M., Kirschner, Marc W.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316466/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10733526/
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