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Inactivation of the p19(ARF) Tumor Suppressor Affects Intestinal Epithelial Cell Proliferation and Integrity
p19(ARF) is a tumor suppressor that is frequently deleted in human cancer. It lies at chromosome 9p21 and shares exons 2 and 3 with p16(ink4a), which is also inactivated by these cancer-associated deletions. The “canonical pathway” by which p19(ARF) is thought to suppress tumorigenesis through activ...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164503/ https://ncbi.nlm.nih.gov/pubmed/18442038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21779 |
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