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Nuclear location of tumor suppressor protein maspin inhibits proliferation of breast cancer cells without affecting proliferation of normal epithelial cells

BACKGROUND: Maspin, which is classified as a tumor suppressor protein, is downregulated in many types of cancer. Several studies have suggested potential anti-proliferative activity of maspin as well as sensitizing activity of maspin for therapeutic cytotoxic agents in breast cancer tissue culture a...

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Detalhes bibliográficos
Main Authors: Machowska, Magdalena, Wachowicz, Katarzyna, Sopel, Mirosław, Rzepecki, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975902/
https://ncbi.nlm.nih.gov/pubmed/24581141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-142
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