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Nuclear location of tumor suppressor protein maspin inhibits proliferation of breast cancer cells without affecting proliferation of normal epithelial cells

BACKGROUND: Maspin, which is classified as a tumor suppressor protein, is downregulated in many types of cancer. Several studies have suggested potential anti-proliferative activity of maspin as well as sensitizing activity of maspin for therapeutic cytotoxic agents in breast cancer tissue culture a...

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Библиографические подробности
Главные авторы: Machowska, Magdalena, Wachowicz, Katarzyna, Sopel, Mirosław, Rzepecki, Ryszard
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975902/
https://ncbi.nlm.nih.gov/pubmed/24581141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-142
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