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Numb controls E-cadherin endocytosis through p120 catenin with aPKC

Cadherin trafficking controls tissue morphogenesis and cell polarity. The endocytic adaptor Numb participates in apicobasal polarity by acting on intercellular adhesions in epithelial cells. However, it remains largely unknown how Numb controls cadherin-based adhesion. Here, we found that Numb direc...

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Detalhes bibliográficos
Main Authors: Sato, Kazuhide, Watanabe, Takashi, Wang, Shujie, Kakeno, Mai, Matsuzawa, Kenji, Matsui, Toshinori, Yokoi, Keiko, Murase, Kiyoko, Sugiyama, Ikuko, Ozawa, Masayuki, Kaibuchi, Kozo
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164458/
https://ncbi.nlm.nih.gov/pubmed/21775625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0274
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