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aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb
In Drosophila, the partition defective (Par) complex containing Par3, Par6 and atypical protein kinase C (aPKC) directs the polarized distribution and unequal segregation of the cell fate determinant Numb during asymmetric cell divisions. Unequal segregation of mammalian Numb has also been observed,...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783459/ https://ncbi.nlm.nih.gov/pubmed/17203073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601495 |
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