Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration

Migrating cells acquire front-rear polarity with a leading edge and a trailing tail for directional movement. The Rac exchange factor Tiam1 participates in polarized cell migration with the PAR complex of PAR3, PAR6, and atypical protein kinase C. However, it remains largely unknown how Tiam1 is reg...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Shujie, Watanabe, Takashi, Matsuzawa, Kenji, Katsumi, Akira, Kakeno, Mai, Matsui, Toshinori, Ye, Feng, Sato, Kazuhide, Murase, Kiyoko, Sugiyama, Ikuko, Kimura, Kazushi, Mizoguchi, Akira, Ginsberg, Mark H., Collard, John G., Kaibuchi, Kozo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2012
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471226/
https://ncbi.nlm.nih.gov/pubmed/23071154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201202041
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