Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides

Mannose-6-phosphate (M6P) is an essential precursor for mannosyl glycoconjugates, including lipid-linked oligosaccharides (LLO; glucose(3)mannose(9)GlcNAc(2)-P-P-dolichol) used for protein N-glycosylation. In permeabilized mammalian cells, M6P also causes specific LLO cleavage. However, the context...

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Main Authors: Gao, Ningguo, Shang, Jie, Huynh, Dang, Manthati, Vijaya L., Arias, Carolina, Harding, Heather P., Kaufman, Randal J., Mohr, Ian, Ron, David, Falck, John R., Lehrman, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164449/
https://ncbi.nlm.nih.gov/pubmed/21737679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0286
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