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Synthesis of High-Mannose Oligosaccharides Containing Mannose-6-phosphate Residues Using Regioselective Glycosylation

Molecular recognition of mannose-6-phosphate (M6P)-modified oligosaccharides by transmembrane M6P receptors is a key signaling event in lysosomal protein trafficking in vivo. Access to M6P-containing high-mannose N-glycans is essential to achieving a thorough understanding of the M6P ligand–receptor...

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Udgivet i:Carbohydr Res
Main Authors: Meng, Bo, Wang, Jun, Wang, Quanli, Serianni, Anthony S., Pan, Qingfeng
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121786/
https://ncbi.nlm.nih.gov/pubmed/30075362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2018.07.005
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