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HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

HIV-1 Vpr promotes nuclear entry of viral nucleic acids in nondividing macrophages and also causes a G(2) cell-cycle arrest. Consistent with its role in nuclear transport, we show Vpr localizes to the nuclear envelope in both human and yeast cells. Like the importin-β subunit of the nuclear import r...

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Bibliografiske detaljer
Main Authors: Vodicka, Marie A., Koepp, Deanna M., Silver, Pamela A., Emerman, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316441/
https://ncbi.nlm.nih.gov/pubmed/9436978
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