HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

HIV-1 Vpr promotes nuclear entry of viral nucleic acids in nondividing macrophages and also causes a G(2) cell-cycle arrest. Consistent with its role in nuclear transport, we show Vpr localizes to the nuclear envelope in both human and yeast cells. Like the importin-β subunit of the nuclear import r...

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Pubblicato in:	Genes Dev
Autori principali:	Vodicka, Marie A., Koepp, Deanna M., Silver, Pamela A., Emerman, Michael
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 1998
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9436978/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.2.175
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