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HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection
HIV-1 Vpr promotes nuclear entry of viral nucleic acids in nondividing macrophages and also causes a G(2) cell-cycle arrest. Consistent with its role in nuclear transport, we show Vpr localizes to the nuclear envelope in both human and yeast cells. Like the importin-β subunit of the nuclear import r...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
1998
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316441/ https://ncbi.nlm.nih.gov/pubmed/9436978 |
| Oznake: |
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