The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

Chinese hamster ovary (CHO)–derived cell lines are the preferred host cells for the production of therapeutic proteins. Here we present a draft genomic sequence of the CHO-K1 ancestral cell line. The assembly comprises 2.45 Gb of genomic sequence, with 24,383 predicted genes. We associate most of th...

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Autori principali: Xu, Xun, Nagarajan, Harish, Lewis, Nathan E, Pan, Shengkai, Cai, Zhiming, Liu, Xin, Chen, Wenbin, Xie, Min, Wang, Wenliang, Hammond, Stephanie, Andersen, Mikael R, Neff, Norma, Passarelli, Benedetto, Koh, Winston, Fan, H Christina, Wang, Jianbin, Gui, Yaoting, Lee, Kelvin H, Betenbaugh, Michael J, Quake, Stephen R, Famili, Iman, Palsson, Bernhard O, Wang, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164356/
https://ncbi.nlm.nih.gov/pubmed/21804562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1932
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