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Model-based analysis of N-glycosylation in Chinese hamster ovary cells

The Chinese hamster ovary (CHO) cell is the gold standard for manufacturing of glycosylated recombinant proteins for production of biotherapeutics. The similarity of its glycosylation patterns to the human versions enable the products of this cell line favorable pharmacokinetic properties and lower...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Krambeck, Frederick J., Bennun, Sandra V., Andersen, Mikael R., Betenbaugh, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423595/
https://ncbi.nlm.nih.gov/pubmed/28486471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175376
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